Knowledge Palette, Inc. Asset Profile

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Year established

2018

Location

Kanagawa Japan

Primary Industry

Healthcare Specialists

About

Based in Kanagawa, Japan, established in 2018 by Masakazu Fukuda and Hiroki Danno, Knowledge Palette is a startup that specializes in improving the quality of cells for use in regenerative medicine. The company solves outstanding issues by applying their proprietary cell measurement and cell cultivation technologies in order to control cell variability and therefore improve the quality of cell-based products. The company's cell measurement technology uses high-precision, single-cell transcriptome (the comprehensive gene expression profile) analysis together with machine learning. Using this technology, it is possible to accurately analyze and determine the cellular composition of target cell populations, such as those in cell-based products, and the kind of indicator genes that characterize the state of cells. This information enables the establishment of high-precision quality control testing and the shipment of only high quality cell-based products. The overall result is stable production and shipping systems with low variability, which also contributes to reducing excess costs. The second method for resolving variability in cell-based products is to fundamentally reduce the variability arising during manufacturing. The company's cell cultivation technology uses high-throughput screening of cell culture conditions. Solution chemistry and robotic technology are used to produce many different culture conditions while comprehensive gene expression profiling and machine learning are used to search for the precise culture conditions that will encourage proliferation of the target cells in a more active state. By culturing under the culture conditions created, it became possible to grow more cells, for longer, and with greater stability. As a result, the amount of variability decreases and it is possible to manufacture cells with little difference between lots. Reduction of rejected lots and significant improvements in yield also help to cut manufacturing costs. Knowledge Palette, Inc. collaborates with pharmaceutical companies and venture companies that are driving improvements in the quality of regenerative medicine as well as research organizations such as universities that are working on the practical application of regenerative medicine.

Current Investors

SPARX Group, Yokohama Capital, ANRI

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Primary Industry

Healthcare Specialists

Sub Industries

Molecular Science, Genetics & Gene Therapy

Website

www.knowledge-palette.com

Verticals

Artificial Intelligence

Company Stage

Series B

Total Amount Raised

Subscriber access only

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