Aclaris Therapeutics, Inc.

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Aclaris Therapeutics, Inc. - overview

Established

2012

Location

Wayne, PA-Pennsylvania, US

Primary Industry

Biotechnology

About

Founded in 2012 and based in Pennslyvania, US, Aclaris Therapeutics, Inc. operates as a biotechnology company that develops small molecule therapies for patients suffering from immuno-inflammatory conditions. The company also operates Confluence Discovery Technologies, Inc. as an indirect, wholly-owned subsidiary that provides full-service drug discovery and early development services for pharma and biotech companies.


In October 2015, Aclaris Therapeutics, Inc. was listed on the Nasdaq under the symbol ACRS for an initial public offering of 5 million shares priced at USD 11 apiece. In November 2024, Aclaris Therapeutics, Inc. raised USD 80 million in PPIPE funding led by returning investor Vivo Capital, with participation from new Rock Springs Capital, Adage Capital Management, Decheng Capital, Logos Capital, and Samsara BioCapital.


Other returning investors Forge Life Science Partners, RA Capital Management, and other unspecified investors also participated in the round. As part of the transaction, the company agreed to sell 35. 5 million shares of common stock purchase at USD 4. 9 per share, for gross proceeds of approximately USD 80 million.


The company's R&D (research and development) team utilizes KINect, a drug discovery platform that enables the generation of diversified immuno-inflammatory therapeutics to attach human kinases with adenosine triphosphate (ATP) site cysteines (human cysteinome) for the treatment of patients with aesthetic, medical dermatology, and immuno-inflammatory diseases. In October 2019, EPI Health acquired RHOFADE, an oxymetazoline hydrochloride cream for rosacea from Aclaris Therapeutics, Inc. As a contract research organization, the company's revenue is generated by providing research partnership and development services of specialty pharmaceuticals for biotechnology companies. The company revenue growth rate decreased by 58.


11 percent from USD 10. 09 million in FY 2018 to USD 4. 23 million in FY 2019. The company continues to develop a multi-state portfolio of drug candidates through KINect, the R&D engine exploring protein kinase regulation for the potential treatment of immuno-inflammatory diseases, such as the oral approach on moderate to severe RA (Rheumatoid Arthritis).


Current Investors

Vivo Capital, Adage Capital Management, Decheng Capital

Primary Industry

Biotechnology

Sub Industries

Biopharmaceuticals, Molecular Science, Genetics & Gene Therapy, Specialty Pharmaceuticals, Pharmaceutical Research & Development

Website

www.aclaristx.com

Company Stage

Mature

Total Amount Raised

Subscriber access only

Aclaris Therapeutics, Inc. - timeline of key events

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Aclaris Therapeutics, Inc. - financials

Fiscal Year EndedDec 31, 2015Dec 31, 2016Dec 31, 2017Dec 31, 2018Dec 31, 2019Dec 31, 2020Dec 31, 2021Dec 31, 2022Dec 31, 2023Dec 31, 2024Dec 31, 2025
Revenue (USD)--1,683,00010,091,0004,227,0006,482,0006,761,00029,752,000---
% Revenue Growth (YoY)---499.6%(58.1%)53.3%4.3%340.1%---
EBITDA (USD)(20,577,000)(48,447,000)(72,021,000)(133,535,000)(104,649,000)(49,588,000)(88,800,000)(89,057,000)---
Operating Income (USD)(20,667,000)(48,567,000)(72,423,000)(135,414,000)(111,058,000)(50,912,000)(89,723,000)(89,854,000)---
Operating Margin--(4303.2%)(1341.9%)(2627.3%)(785.4%)(1327.1%)(302.0%)---
% EBITDA Margin--(4279.3%)(1323.3%)(2475.7%)(765.0%)(1313.4%)(299.3%)---
NET Income (USD)(20,563,000)(48,079,000)(68,523,000)(132,738,000)(161,354,000)(51,015,000)(90,865,000)(86,908,000)---
% Net Margin--(4071.5%)(1315.4%)(3817.2%)(787.0%)(1344.0%)(292.1%)---

Aclaris Therapeutics, Inc. - deals

Deals TypeDeal StatusTarget (s)Deal DateInvestor(s)Seller(s)Deal size (Mn)Enterprise value (Mn)Post-money valuation (Mn)EBITDA multiple (x)Revenue multiple (x)Lead partner (s)
PIPECompletedAclaris Therapeutics, Inc.-
Private Placement/Follow onCompletedAclaris Therapeutics, Inc.-
Private Placement/Follow onCompletedAclaris Therapeutics, Inc.-
Venture DebtCompletedAclaris Therapeutics, Inc.-
Private Placement/Follow onCompletedAclaris Therapeutics, Inc.-

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Aclaris Therapeutics, Inc. - employee data

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